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BIOASSAY AND BIOMOLECULAR IDENTIFICATION, SORTING, AND COLLECTION METHODS USING MAGNETIC MICROSPHERES

机译:利用磁性微球进行生物测定和生物分子的鉴定,分类和收集方法

摘要

The present invention provides a process of separating a sample comprising attaching a different receptor agent to at least two distinct populations of magnetic microspheres with a specific range of magnetic moments; combining a target sample with said distinct populations of magnetic microspheres containing different attached receptor agents together for a period of time sufficient to allow for binding between attached receptor agents and target species within said target sample to form one or more receptor agent-target species complexes; and sorting said distinct populations of magnetic microspheres containing different receptor agent-target species complexes by passing through a magnetic separator.
机译:本发明提供了一种分离样品的方法,该方法包括将不同的受体试剂附着到具有特定范围的磁矩的至少两个不同的磁性微球体上。将目标样品与所述包含不同的附着受体试剂的磁性微球的不同群体组合在一起足够长的时间,以允许附着的受体试剂与所述目标样品内的靶物质之间结合,以形成一种或多种受体试剂-靶物质复合物;并通过磁分离器对包含不同受体试剂-目标物质复合物的磁性微球的所述不同种群进行分选。

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