MAMMAL 2P DOMAIN MECHANO-SENSITIVE K+ CHANNEL, CLONING AND APPLICATIONS THEREOF
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机译:哺乳动物2P域机械敏感K +通道,克隆及其应用
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摘要
This invention relates to a protein including a mammalian K+ channel with two pore domains, designated TREK2, that produces currents whose current-voltage relationship is weakly inward rectifying in high symmetrical K+ conditions. This invention further relates to the isolation and characterization of such protein, as well as a method using TREK2 to identify bioactive compounds having anesthetic properties.
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