首页> 外国专利> METHOD FOR THE SELECTIVE SURVIVAL OR SELECTIVE GROWTH OF A TARGET CELL BY THE USE OF A CONJUGATE, ITS USE IN THE THERAPEUTICS AND/OR DIAGNOSTICS

METHOD FOR THE SELECTIVE SURVIVAL OR SELECTIVE GROWTH OF A TARGET CELL BY THE USE OF A CONJUGATE, ITS USE IN THE THERAPEUTICS AND/OR DIAGNOSTICS

机译:结合物的选择性存活或选择性生长的方法及其在治疗和/或诊断中的用途

摘要

The invention is in particular related to a method for the selective survival or selective growth of a target cell comprising the steps of: a) contacting the target cell with a conjugate compound A-B, wherein A is a selective antibody or antibody derivative recognizing the target cell and B is a biotic agent able to at least partially inactivate an anti-bios agent, said anti-bios agent is able to inhibit the growth of cells; and b) contacting the target cell with the anti-bios agent. The present invention also relates to said conjugate on its own, a selection medium for cells comprising said conjugate and cells that are selected or recognized using a method or conjugate according to the present invention. The present invention further elucidates a pharmaceutical compound or composition, a kit for the detection of a target cell or for the diagnosis of diseases caused by the target cell or a product that can be used in the therapy of infectious related diseases comprising a conjugate according to present invention.
机译:本发明特别涉及用于靶细胞的选择性存活或选择性生长的方法,其包括以下步骤:a)使靶细胞与缀合物AB接触,其中A是识别靶细胞的选择性抗体或抗体衍生物。 B是能够至少部分灭活抗生物剂的生物剂,所述抗生物剂能够抑制细胞的生长; b)使靶细胞与抗生物剂接触。本发明还涉及所述缀合物本身,用于包含所述缀合物的细胞的选择培养基以及使用根据本发明的方法或缀合物选择或识别的细胞。本发明进一步阐明了药物化合物或组合物,用于检测靶细胞或用于诊断由靶细胞引起的疾病的试剂盒或可用于治疗感染相关疾病的产品,其包含根据权利要求1的缀合物。本发明。

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