BROAD SPECTRUM TUMOR SUPPRESSOR GENES GENE PRODUCTS AND METHODS FOR TUMOR SUPPRESSION GENE THERAPY

摘要

The present invention relates to a wide range of tumor suppressor genes and proteins expressed by genes in appropriate host cells. The protein is a second in-frame AUG codon initiated retinoblastoma protein having a molecular weight of about 94 kD. The present invention relates to a method for treating a mammal having a disease characterized by abnormal cell proliferation such as cancer or tumor cells. Treatment consists of administering a p94 ^RB expression vector or p94 ^RB protein into a host cell into the cell in need of treatment.