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Inhibition of tumor necrosis factor and nitric oxide production by retinoic acid

机译:维甲酸抑制肿瘤坏死因子和一氧化氮的产生

摘要

The present invention is directed to a novel method of inhibiting the production of two important modulators of cellular action, tumor necrosis factor and nitric oxide, and treating pathophysiological conditions characterized by undesirable production or concentrations of tumor necrosis factor or nitric acid. It is about. The methods of the present invention use retinoic acid compounds. Most preferred retinoic acid is all trans-retinoic acid.
机译:本发明涉及抑制细胞作用的两种重要调节剂,肿瘤坏死因子和一氧化氮的产生,以及治疗以肿瘤坏死因子或硝酸的不期望产生或浓度为特征的病理生理状况的新颖方法。关于。本发明的方法使用视黄酸化合物。最优选的视黄酸是全反式视黄酸。

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