Labeled chemotactic peptides for imaging lesion sites of infection or inflammation

摘要

The present invention provides a method of detecting an infection or inflammation site, and a detectable labeled therapeutic or therapeutically incorporated chemotactic peptide that is substantially accumulated in an infected or inflamed area in an amount effective for diagnosis or treatment. A method for treating infection or inflammation in a subject by administering to a subject wherein said chemotactic peptide is of the general structure XY-Leu-Phe- [2] nW (where X is an aminoprotecting group and Y is an amino acid residue and Z is a spacer sequence And n is 0 or 1 and W is a label or attached substituent.