Protein-linked nanoparticles with coupled apolipoprotein E to overcome the blood-brain barrier and process for their production

摘要

The invention relates to nanoparticles for penetration of the blood-brain barrier, characterized in that they consist of a hydrophilic protein or a combination of hydrophilic proteins, preferably serum albumen, most preferably of human origin, which is coupled to apolipoprotein B. the invention also relates to methods for the production of said nanoparticles.