NEUROTROPHIC PEPTIDES OF THE ACTIVITY-DEPENDENT NEUROTROPHIC FACTOR

摘要

The present invention relates generally to Activity Dependent Neurotrophic Factor (ADNF). More particularly, the present invention relates to a family of polypeptides derived from ADNF that exhibit neuroprotective/neurotrophic action on neurons originating in the central nervous system and to uses thereof for the treatment of neurological deficiencies and for the prevention of cell death. The present invention also relates to pharmaceutical compositions designed to prevent neuronal cell death.