NITROGEN MONOXIDE SYNTHETASE INHIBITOR

摘要

PPROBLEM TO BE SOLVED: To obtain a compound excellent in nitrogen monoxide synthetase inhibiting action. PSOLUTION: The nitrogen monoxide synthetase inhibitor comprises as an effective ingredient a compound represented by formula (I) (wherein the ring A is an optionally substituted hydrocarbyl or heterocyclic ring; X is a single bond, -O-, -N(RSP4/SP)-, or the like; RSP1/SPis hydrogen, a lower alkyl or an aryl-lower alkyl; RSP2/SPand RSP3/SPare each hydrogen, a lower alkyl, or the like; RSP4/SPand RSP5/SPare each hydrogen, a lower alkyl, a carbamoyl, or the like; (n) is 1, 2 or 3; and (m) is an integer of 1-5), a pharmaceutically acceptable salt thereof, or a solvated compound thereof. PCOPYRIGHT: (C)2004,JPO&NCIPI