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Pharmaceutical or cosmetic compositions for inhibiting the migration of Langerhans cells and use of MMP inhibitors and PKC inhibitors

机译:用于抑制朗格汉斯细胞迁移的药物或化妆品组合物以及MMP抑制剂和PKC抑制剂的用途

摘要

The invention concerns a pharmaceutical or cosmetic composition, characterized in that it comprises at least a compound for inhibiting Langerhans' cell migration, said active compound being selected in the group consisting of protein kinase C (PKC) inhibiting compounds, matrix metalloprotease (MMP) inhibiting compounds, and combinations thereof, and at least a pharmaceutically or cosmetically acceptable carrier. Said composition enables to inhibit considerably Langerhans' cell migration induced by the presence of an allergenic agent.
机译:本发明涉及药物或化妆品组合物,其特征在于其至少包含用于抑制朗格汉斯细胞迁移的化合物,所述活性化合物选自蛋白激酶C(PKC)抑制性化合物,基质金属蛋白酶(MMP)抑制性的化合物。化合物及其组合,以及至少一种药学或美容上可接受的载体。所述组合物能够显着抑制由变应原剂的存在诱导的朗格汉斯细胞迁移。

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