METHOD FOR ASSAYING DRUG-METABOLIZING ENZYME ACTIVITY, METHOD FOR EVALUATING ACTIVITY INHIBITION OF DRUG-METABOLIZING ENZYME, AND COMPOSITION FOR THE METHODS

摘要

PROBLEM TO BE SOLVED: To provide a method for assaying the activity of a drug-metabolizing enzyme important in a drug metabolic reaction in an organism and a method for evaluating activity inhibitory effect of a chemical substance on a drug-metabolizing enzyme and to obtain a composition for the methods.;SOLUTION: The method for assaying the drug-metabolizing enzyme activity comprises treating an intrinsic unmodified substrate with the drug-metabolizing enzyme and assaying the formed product.;COPYRIGHT: (C)2004,JPO