Revelation characteristic and inviting occurrence mutation and the Cre fusion protein of the latent supuraishingu region of Cre in order to improve

摘要

As for this invention, being the DNA arrangement which the mutant of rikonbinaze Cre of bacteriophage P1 the cord/code is done, the latent supuraishingu region of specification among those, nothing regards the aforementioned DNA arrangement which is functionated with the base displacement which alters Cre protein arrangement. This invention furthermore regards the DNA arrangement which the fusion protein which is derived with from the above-mentioned Cre mutant and the ligand connection domain of the receptor protein the cord/code is done. This invention furthermore, the vector which contains the above-mentioned DNA arrangement, the microbe and the toransujienitsuku living thing, commonly regards the Cre mutant and the Cre fusion protein which the cord/code are done with the above-mentioned DNA arrangement.