NEW 3-HYDROXYBUTYRIC ACID DEHYDROGENASE GENE, METHOD FOR PRODUCING THE SAME ENZYME, METHOD FOR MEASURING KETONE BODY BY USING THE SAME ENZYME AND COMPOSITION FOR MEASUREMENT

摘要

PROBLEM TO BE SOLVED: To provide a gene encoding a new 3-hydroxybutyric acid dehydrogenase, a new 3-hydroxybutyric aciddehydrogenase, a method for producing the enzyme by a gene recombinant technology and a composition for measuring a ketone body by using the same enzyme. ;SOLUTION: This gene encodes the following bacterium-derived 3- hydroxybutyric acid dehydrogenase as a protein of (a) or (b). (a) A protein having a specific amino acid sequence. (b) A protein consists of an amino acid sequence obtained by lacking, substituting or adding 1 or several amino acids in the amino acid sequence (a), and has the 3-hydroxybutyric acid dehydrogenase activity.;COPYRIGHT: (C)2004,JPO