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Phosphatidylcholine as medication with protective effect large intestinal mucosa

机译:磷脂酰胆碱作为具有保护作用的药物对大肠粘膜有保护作用

摘要

The presented invention relates to a medication containing a therapeutically effective amount of phosphatidylcholine as active substrate for treatment of disease where phosphatidylcholine has an advantageous, protective effect on the mucosa of large intestine. The invention also relates to the use and application form of phosphatidylcholine for local treatment of inflammation of the large intestine and prophylaxis against cancer of the colon. Phosphatidylcholine can be administered as a rectal installation for local treatment of inflammation (in rectum or pouch) as well as in orally administered delayed-release form. The orally administered, delayed-release form of phosphatidylcholine prevents absorption in upper intestine and thus provides targeted release in the lower sections of the small intestine or colon.
机译:本发明涉及一种药物,该药物含有治疗有效量的磷脂酰胆碱作为用于治疗疾病的活性底物,其中磷脂酰胆碱对大肠的粘膜具有有利的保护作用。本发明还涉及磷脂酰胆碱用于局部治疗大肠发炎和预防结肠癌的用途和应用形式。磷脂酰胆碱可以直肠给药,可以局部治疗炎症(直肠或囊袋),也可以口服缓释形式。口服给药的磷脂酰胆碱的延迟释放形式阻止了在上层小肠中的吸收,从而在小肠或结肠的下层中提供了靶向释放。

著录项

  • 公开/公告号US6677319B1

    专利类型

  • 公开/公告日2004-01-13

    原文格式PDF

  • 申请/专利权人 STREMMEL WOLFGANG;

    申请/专利号US20010762195

  • 发明设计人 WOLFGANG STREMMEL;

    申请日2001-02-05

  • 分类号A01N572/60;

  • 国家 US

  • 入库时间 2022-08-21 23:15:03

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