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Imaging cell death in vivo using non-radionuclide contrast agents
Imaging cell death in vivo using non-radionuclide contrast agents
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机译:使用非放射性核素造影剂在体内成像细胞死亡
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摘要
An annexin, annexin analogue or phosphatidylserine binding compound (PSC) labeled with an MR, CT, or optical contrast agent. The conjugate is administered into a subject and specifically binds to the surface of apoptotic and necrotic cells. The subject is imaged using conventional MRI, CT and optical imaging techniques and dead and dying tissue is identified. The identification and development of analogues specific for phosphatidylserine for purposes of non-invasive imaging of dead or dying cells.
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