Methods to select a sequence of DNA with a quality modulator of transcription of gene, to identify a sequence of DNA with a quality of repression of transcription of the gene.To detect the presence of a sequence star and a star inside element of a sequence of nucleic acid, to determine if a sequence of nucleic acid sequence comprises a star, and,To produce a gene product in a cell, sequence of nucleic acid isolation and / or recombinant DNA sequence, sequence star, collection, the construction of DNA.The use of a building or sequence of DNA, and, a library of nucleic acids isolated and / or recombinant

摘要

The invention is concerned with the systematic elucidation and identification of regulatory sequences. The invention provides among others screenings and detection methods with which regulatory sequences can be identified. The invention further provides regulatory sequences and use thereof in various fields such as, but not limited to protein production, diagnostics, transgenic plants and animals, and the therapeutic field.