Method for affecting sleep-related and sleep behaviors

摘要

"METHOD FOR AFFECTING SLEEP AND SLEEP-RELATED BEHAVIOR". The present invention relates to the disclosure of a method of affecting sleep and sleep-related behaviors in a daytime rhythm mammal by reducing basal activity of the hypothalamopituitary-adrenal axis by administering an effective amount of a sensory regime. . Such reduction may be accomplished by reducing at least one of the following: a. the average total daily amount of adrenocortical hormone or b. the average total daily amount of adrenocortical hormone minus measured by integration of adrenocortical hormone at morning peak. Preferably, such reduction also includes reducing at least one of the following: C. the level of adrenocortical hormone 4 to 8 hours after awakening; d. the level of adrenocortical hormone in the time period prior to bedtime or e. the level of adrenocortical hormone below said onset of sleep threshold.