首页> 外国专利> Pharmaceutical composition comprising undifferentiated mesenchymal cells and fibroblasts autologous autologous (UMC), substantially free of Serum Protein, Preparation methodUseful to REPAIR DAMAGED tissue.

Pharmaceutical composition comprising undifferentiated mesenchymal cells and fibroblasts autologous autologous (UMC), substantially free of Serum Protein, Preparation methodUseful to REPAIR DAMAGED tissue.

机译:包含未分化的间充质细胞和自体成纤维细胞(UMC),基本不含血清蛋白的药物组合物,其制备方法可用于修复受损的组织。

摘要

The present invention provides compositions and methods for correcting cosmetic, aesthetic, and degenerative defects in the skin, soft tissue, and bone of a subject. In particular, methods of the invention involve the injection or implantation of autologous UMC, fibroblasts, and/or kcratinocytes into the tissue (e.g., subcutaneous tissue) adjacent or subadjacent to a defect or at the site of a defect. The cells that are injected, as provided herein, are histocompatible with the subject (e.g., are autologous) and have been expanded by passage in a cell culture system.
机译:本发明提供了用于纠正对象的皮肤,软组织和骨骼中的美容,美学和退化缺陷的组合物和方法。特别地,本发明的方法涉及将自体UMC,成纤维细胞和/或角质形成细胞注射或植入到邻近缺陷或在缺陷附近或在缺陷部位的组织(例如皮下组织)。如本文所提供的,被注射的细胞与受试者是组织相容的(例如,是自体的),并且已经通过在细胞培养系统中传代而扩增。

著录项

  • 公开/公告号CL2003002417A1

    专利类型

  • 公开/公告日2004-08-27

    原文格式PDF

  • 申请/专利权人 ISOLAGEN TECHNOLOGIES INC.;

    申请/专利号CL20030002417

  • 发明设计人 MARKO OLGA;BOSS WILLIAM;

    申请日2003-11-21

  • 分类号A61F2/02;A61K35/12;A61L27/38;C12N5/06;C12N5/08;

  • 国家 CL

  • 入库时间 2022-08-21 23:11:44

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