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SUBSTITUTED N-PHENYL 2 - HYDROXY - 2 - METHYL - 3,3,3 - TRIFLUOROPROPANAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, PROCESSES FOR THEIR PREPARATION AND USE THEREOF AS MEDICAMENTS AND IN MANUFACTURE OF MEDICAMENTS FOR ELEVATING PDH ACTIVITY IN WARM-BLOODED ANIMALS
SUBSTITUTED N-PHENYL 2 - HYDROXY - 2 - METHYL - 3,3,3 - TRIFLUOROPROPANAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, PROCESSES FOR THEIR PREPARATION AND USE THEREOF AS MEDICAMENTS AND IN MANUFACTURE OF MEDICAMENTS FOR ELEVATING PDH ACTIVITY IN WARM-BLOODED ANIMALS
Compounds of formula (I) wherein R is methyl or mesyl; and pharmaceutically acceptable salts and in vivo hydrolysable esters thereof are described. Also described are processes for their preparation, pharmaceutical compositions containing it and their use in producing an elevation of PDH activity in a warm-blooded animal.
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