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Regulation system of expression using nuclear PPAR receptors
Regulation system of expression using nuclear PPAR receptors
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机译:利用核PPAR受体调节表达系统
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摘要
Methods and compositions for the pharmacological regulation of the expression of transgenes. A composition comprising: (a) a first element comprising a nucleic acid of interest under the control of an inducible promoter comprising an element containing a response element to a Peroxisome Proliferator-Activated Receptor (PPAR) and a minimal transcriptional receptor; and (b) a second element comprising a nucleic acid coding for a PPAR under the control of a transcriptional promoter, for simultaneous, separate or prolonged use And the use of said compositions and methods in the experimental, clinical, therapeutic or diagnostic fields.
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