SUBSTITUTED BENZAMIDINE DERIVATIVES WITH AMINO ACIDS AND HYDROXYACIDES DERIVATIVES AND THEIR USE AS ANTICOAGULANTS

摘要

This invention is directed to benzamidine derivatives substituted by amino acid and hydroxy acid derivatives which are useful as anti-coagulants. This invention is also directed to pharmaceutical compositions containing the compounds of the invention, and methods of using the compounds to treat disease-states characterized by thrombotic activity.