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METHOD FOR COMBINATIONAL REACTION FINDING FOR THE PRODUCTION OF USEFUL PRODUCTS
METHOD FOR COMBINATIONAL REACTION FINDING FOR THE PRODUCTION OF USEFUL PRODUCTS
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机译:生产有用产品的组合反应发现方法
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摘要
The invention relates to a method for the algorithmic search for and production of biologically active chemical compounds. Said method comprises the following steps: (1) producing an algorithmic library of different multicomponent reactions; starting from a library of suitable and diverse types of chemical starting compounds; (2) biologically testing said library; (3) identifying suitable multicomponent reactions from this range of suitable reactions; (4) choosing a multitude of chemical starting substances of those types that are required for the identified and suitable multicomponent reactions; (5) finding optimum combinations from said constructed chemical range of suitable multicomponent reactions by (6) algorithmically producing and biologically testing compounds of said library. The inventive method is exemplified by way of the example of finding new antibiotically active polyketoidous compounds.
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