PIRROLIDINE DERIVATIVES THAT HAVE INHIBITING ACTIVITY OF PHOSPHOLIPASE A2.

摘要

The invention relates to compounds having the formula (I) in which, for example, R {sup, 1} is optionally substituted aralkyl, Z is a nitrogen atom that is optionally substituted with alkyl, X {sup, 1} es-CH2NHCO-, X {sup, 2} is phenylene, X {sup, 3} is a bond, Y {sup, 2} is an optionally substituted aryl, B s an oxygen atom, or its pharmaceutically acceptable salts or the these hydrate, and pharmaceutical compositions containing them as active ingredients.