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PHARMACOLOGICAL AGENT THAT INCLUDES PICOLINIC ACID, FUSARIC ACID AND ITS DERIVATIVES

机译:包含苦味酸,铁酸及其衍生物的药理代理

摘要

A pharmacologically active metal ion chelating agent for the treatment of a disease, disorder or condition chosen from the group consisting of hepatitis C infections, angiogenesis, sunburn, decreased immune function, metastatic colon cancer and upper respiratory infections, where the disease it is mediated by a protein having a metal ion-protein complex, the agent having the following structure: or a respective pharmacologically acceptable salt, wherein R1, R2, R3 or R4 are selected from the group consisting of a sixteen amino acid peptide, carboxyl group, methyl group, ethyl group, propyl group, isopropyl group, butyl group, isobutyl group, secondary butyl group, tertiary butyl group, pentyl group, isopentyl group, neopentyl group, fluorine, chlorine, bromine, iodine and hydrogen.
机译:一种药物活性金属离子螯合剂,用于治疗疾病,病症或病状,选自丙型肝炎感染,血管生成,晒伤,免疫功能降低,转移性结肠癌和上呼吸道感染,其中该疾病是由以下疾病介导的具有金属离子-蛋白质复合物的蛋白质,具有以下结构的试剂:或相应的药理学上可接受的盐,其中R1,R2,R3或R4选自十六个氨基酸肽,羧基,甲基,乙基,丙基,异丙基,丁基,异丁基,仲丁基,叔丁基,戊基,异戊基,新戊基,氟,氯,溴,碘和氢。

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