USEFUL AMINOSTEROL COMPOUNDS AS INHIBITORS OF THE SODIUM / PROTON EXCHANGER (NHE), PHARMACEUTICAL METHODS AND COMPOSITIONS THAT USE THESE INHIBITORS AND PROCESSES TO EVALUATE THE INHIBITING EFFICIENCY OF NHE OF SUCH COMPOUNDS.

摘要

AMINOSTEROL COMPOUNDS DESCRIBED THAT ARE USEFUL AS INHIBITORS OF THE SODIUM / PROTON EXCHANGER (NHE). METHODS ARE ALSO INCLUDED FOR USING SUCH AMINOSTEROL COMPOUNDS, INCLUDING THOSE THAT USE COMPOUNDS THAT ARE INHIBITORS OF AN NHES SPECTRUM, AS WELL AS THOSE THAT USE COMPOUNDS THAT ARE INHIBITORS ONLY OF A SPECIFIC NHE. TECHNICAL ASSESSMENTS AND ADVANTAGE SCRUTINY TESTS ARE DISCOVERED TO EVALUATE THE THERAPEUTIC ACTIVITY OF A COMPOUND.