METHOD FOR THE GENE REGULATION AT BOTH TRANSCRIPTION AND POST-TRANSCRIPTION LEVELS

摘要

A method for regulating a target gene, which comprises introducing into a cell a zinc finger protein binding to a promoter of the target gene or a DNA encoding same, and a RNA molecule binding to an mRNA transcribed from the target gene to inhibit the expression of said target gene; and a composition for regulating a target gene comprising the zinc finger protein or a DNA encoding same, and the RNA molecule provide a substantially complete gene regulating effect due to the synergistic effect of the combination of ZFP and RNAi technologies.