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Mammalian transgenesis by intracytoplasmic sperm injection
Mammalian transgenesis by intracytoplasmic sperm injection
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机译:通过胞浆内精子注射进行哺乳动物转基因
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摘要
Coinjection of unfertilized mouse oocytes with sperm heads and exogenous nucleic acid encoding a transgene results in transgene-expressing embryos, reflecting nucleic acid-sperm head association before coinjection. Nonselective transfer to surrogate mothers of embryos resulting from coinjection produced offspring expressing the integrated transgene.
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