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Polymer-coated stents, methods for preparing same and their use for restenosis prevention
Polymer-coated stents, methods for preparing same and their use for restenosis prevention
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机译:聚合物涂层支架,其制备方法及其在预防再狭窄中的用途
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摘要
A polymer-coated stent comprises a stent base coated with a polymer containing hydrophilic substances (I) with strong affinity for therapeutic agents. Claimed manufacture of the stent involves gas phase coating of the metal base with a functional polymer at elevated temperature and reduced pressure; a complexing agent (as (I)) is then bound to the polymer's functional groups (optionally after treatment with a solution that containing spacer molecules). Alternatively the stent is coated by plasma polymerisation, followed by treatment with the complexing agent (optionally after application of the spacer molecule).
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