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Process for producing array plate for biomolecules having hydrophilic and hydrophobic regions

机译:生产具有亲水和疏水区域的生物分子的阵列板的方法

摘要

A method for manufacturing an array plate for biomolecules and a method for manufacturing a biochip using this array plate are provided. The array plate manufacturing method includes: (a) coating a surface of a substrate (1) with a hydrophobic material to form a hydrophobic layer (3); (b) etching the hydrophobic layer through an etch mask (4) placed thereon to form a hydrophilic binding site (5); (c) removing the remaining etch mask; and (d) processing the remaining region of the hydrophobic layer (3) to recover its original hydrophobic properties. The biochip manufacturing method includes processing the surface of the hydrophilic binding site (5) of an array plate manufactured using the method, and applying a solution containing biomolecules to the surface of the hydrophilic binding site.
机译:提供了一种用于制造生物分子的阵列板的方法和一种使用该阵列板的生物芯片的制造方法。阵列板的制造方法包括:(a)用疏水材料涂覆基板(1)的表面以形成疏水层(3); (b)通过置于其上的蚀刻掩模(4)蚀刻疏水层以形成亲水结合位点(5); (c)去除剩余的蚀刻掩模; (d)处理疏水层(3)的其余区域以恢复其原始的疏水特性。生物芯片的制造方法包括对使用该方法制造的阵列板的亲水性结合位点(5)的表面进行处理,然后将含有生物分子的溶液涂布于亲水性结合位点的表面。

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