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REPLACING LIVER CELLS WITH BONE MARROW-DERIVED CELLS FOR TREATING DISEASE AND EXPRESSING THERAPEUTIC GENES
REPLACING LIVER CELLS WITH BONE MARROW-DERIVED CELLS FOR TREATING DISEASE AND EXPRESSING THERAPEUTIC GENES
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机译:用骨髓来源的细胞替代肝细胞以治疗疾病和表达治疗基因
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摘要
The invention provides a method for introducing a population of Kupffer cells into an individual. The method includes the steps of (a) administering to an individual a Kupffer cell toxin, wherein the toxin ablates a first population of Kupffer cells of the individual, and (b) administering to the individual a population of Kupffer cell progenitors, wherein the population of Kupffer cell progenitors replaces the first population of Kupffer cells, thereby providing a second population of Kupffer cells.
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