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TUMOR REJECTION ANTIGEN PRECURSORS, TUMOR REJECTION ANTIGENS AND USES THEREOF

机译:肿瘤排斥抗原前体,肿瘤排斥抗原及其用途

摘要

The invention relates to an isolated DNA sequence which codes for an antigen expressed by tumor cells which is recognized by cytotoxic T cells, leading to lysis of the tumor which expresses it. Also described are cells transfected by the DNA sequence, and various therapeutic and diagnostic uses arising out of the properties of the DNA and the antigen for which it codes.
机译:本发明涉及分离的DNA序列,其编码由肿瘤细胞表达的抗原,该抗原被细胞毒性T细胞识别,导致表达该肿瘤的肿瘤裂解。还描述了被DNA序列转染的细胞,以及由于DNA及其所编码的抗原的性质而引起的各种治疗和诊断用途。

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