SINGLE NUCLEOTIDE POLYMORPHIC DISCRIMINATION BY ELECTRONIC DOT BLOT ASSAY ON SEMICONDUCTOR MICROCHIPS

摘要

Quick detection single nucleotide polymorphism (SNP) of one kind is detected that and is disclosed using the circuit on silicon microchip. This method provides the accurate DNA samples for distinguishing amplification with electrode (test site) selected by electron assistant transhipment, concentration and connection DNA. Test site tissue samples composition is a series of to be distinguished from each other because verifying the SNP genotype using internal control double labelling indicator includes wild type and mismatch. The method is used to distinguish between the SNP equipotential mannose binding proteins in complicated plinth.