Controlled release of ketorolac tromethamine using pellet-tape dosage form

摘要

PURPOSE: Provided is a controlled release pellet containing ketorolac tromethamine, thereby reducing dosage and consequently increasing drug stability and decreasing side effects. CONSTITUTION: The controlled release pellet containing ketorolac tromethamine characteristically consists of a crystalline core(1) having a size of 300-1000 micrometer, an inner layer(2) including ketorolac tromethamine, and a controlled release type of outer layer(3) containing Eudragit as an essential ingredient and optionally a water-soluble polymer.