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APPLICATION OF SPECIFIC ANTAGONIST OF 5HT2A-RECEPTORS FOR PREPARING DRUGS USEFUL FOR TREATMENT OF SLEEP APNEA SYNDROME
APPLICATION OF SPECIFIC ANTAGONIST OF 5HT2A-RECEPTORS FOR PREPARING DRUGS USEFUL FOR TREATMENT OF SLEEP APNEA SYNDROME
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机译:5HT 2A Sub>受体特异性拮抗剂在制备治疗睡眠呼吸暂停综合症药物中的应用
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摘要
FIELD: medicine, pharmacy. SUBSTANCE: invention relates to preparing drugs that can be used for treatment of sleep apnea syndrome. Invention proposes to use specific antagonists of 5HT2A-receptors, such as 1-(2-fluorophenyl)-3-(4-hydroxyphenyl)-prop-2-ene-1-one-O-(2- dimethylaminoethyl)-oxime or its pharmaceutically acceptable salts. Method provides significant reduction of index apnea-hypnea in such patients. EFFECT: valuable medicinal properties of antagonist. 4 cl, 4 ex
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机译:领域:医学,药学。物质:本发明涉及制备可用于治疗睡眠呼吸暂停综合症的药物。本发明提出使用5HT 2A Sub>-受体的特异性拮抗剂,例如1-(2-氟苯基)-3-(4-羟基苯基)-丙-2-烯-1-酮-O-( 2-二甲基氨基乙基)-肟或其药学上可接受的盐。该方法可显着降低此类患者的指数呼吸暂停-呼吸不足。功效:拮抗剂的重要药用特性。 4 cl,4 ex
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