呼出气一氧化氮、气道阻力、肺功能在睡眠呼吸暂停低通气综合征患者中的应用以及白三烯受体拮抗剂的治疗效果

摘要

The study aims to measure the exhaled nitric oxide(eNO)from different parts of airway,airway resistance and pulmonary function in OSAHS patients and explore their potential application,especially eNO,in clinical setting.eNO is an effective marker for upper airway obstructive episodes due hypoxemiacausing local oropharyngeal inflammation and can serve as an indicator in the diagnosis andmanagement of OSAHS together with airway resistance. Through its ability to amplify oxidative andnitrosative stress, may be suggested to have a pathogenetic role in OSAHSA.