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PHARMACEUTICAL COMPOSITION WITH CYTOKINE AND IMMUNOMODULATING EFFECTS

机译:含细胞因子的药物成分和免疫调节作用

摘要

FIELD: medicine, chemical- -pharmaceutical industry, pharmacy. SUBSTANCE: invention relates to pharmaceutical composition eliciting cytokine and immunomodulating effect used for prophylaxis and treatment of diseases caused by disorders of immunologic functions. Addition of copolymer of 1,4-ethylenepiperazine N-oxide and (N-carboxyethyl)-1,4-ethylenepiperazinium bromide to an active substance in pharmaceutical composition consisting of at least one cytokine or conjugation with the latter allows creating the novel immunotherapeutic preparation with the enhanced effectiveness as compared with the known analogs. Advantage of invention involves the creation of preparation eliciting ability to modulate cytokine effect and it comprises new additional biological properties also. EFFECT: enhanced effectiveness of composition, valuable medicinal properties. 9 tbl, 8 ex
机译:领域:医药,化学-制药工业,药学。发明领域本发明涉及引起细胞因子和免疫调节作用的药物组合物,其用于预防和治疗由免疫功能异常引起的疾病。在由至少一种细胞因子或与之结合的药物组合物中的活性物质中加入1,4-乙烯哌嗪N-氧化物和(N-羧乙基)-1,4-乙烯哌嗪溴化物的共聚物可制得新颖的免疫治疗制剂与已知类似物相比具有增强的功效。本发明的优点涉及产生调节细胞因子作用的制剂引发能力,并且它还包括新的附加生物学特性。功效:增强了组合物的功效,有价值的药用特性。 9汤匙,8前

著录项

  • 公开/公告号RU2222345C2

    专利类型

  • 公开/公告日2004-01-27

    原文格式PDF

  • 申请/专利权人

    申请/专利号RU20020101171

  • 申请日2002-01-21

  • 分类号A61K38/19;A61K39/39;A61P37/00;

  • 国家 RU

  • 入库时间 2022-08-21 22:45:14

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