首页>
外国专利>
METHOD FOR IMPROVED FUNCTIONAL RECOVERY OF MOTOR COORDINATION, LANGUAGE OR SENSUAL ASSESSMENT AFTER TRAUMA OR ISCHEMIA OF THE CNS
METHOD FOR IMPROVED FUNCTIONAL RECOVERY OF MOTOR COORDINATION, LANGUAGE OR SENSUAL ASSESSMENT AFTER TRAUMA OR ISCHEMIA OF THE CNS
展开▼
机译:CNS创伤或缺血后改善电机协调,语言或感官评估的功能恢复的方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention provides methods and compositions for treatment of mammals afflicted with an ischemic or traumatic injury of the central nervous system. The present invention capitalizes in part upon the discovery that administration of a morphogen to such a mammal provides significant improvement in central nervous system function, even when administered after central nervous system tissue has been damaged. The methods involve the administration of dimeric proteins defined as morphogens, inducers of these morphogens, or agonists of the corresponding morphogen receptors, or implantation of cells stimulated by exposure to the morphogens. The proteins defined as morphogens comprise a structurally and functionally distinct family within the TGT- beta superfamily. Osteogenic protein-1 (OP-1) is considered to be an exemplary and preferred member of this morphogen family.
展开▼