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Novel enzymatic substrates for the detection of pseudomonas aeruginosa, compositions containing them and method of detection of this species

机译:用于检测铜绿假单胞菌的新型酶促底物,包含它们的组合物和该物种的检测方法

摘要

The invention concerns an enzymatic substrate consisting of a target portion and a marker portion, the target portion being separated from the marker portion by hydrolysing the substrate, said target portion characterising the desired enzymatic activity. The invention also concerns a composition containing at least such a substrate and a method for detecting the iPseudomonas aeruginosa/i bacterial species. The target portion of the substrate enables to reveal a beta -alanine aminopeptidase enzymatic activity and the marker portion is a molecule revealing the hydrolysis reaction. The invention is particularly useful in the field of diagnosis.
机译:本发明涉及由靶标部分和标记物部分组成的酶促底物,通过水解底物使靶标部分与标记物部分分离,所述靶标部分表征所需的酶活性。本发明还涉及至少包含这种底物的组合物和用于检测铜绿假单胞菌细菌种类的方法。底物的靶标部分能够揭示β-丙氨酸氨基肽酶的酶促活性,而标记物部分是揭示水解反应的分子。本发明在诊断领域特别有用。

著录项

  • 公开/公告号FR2801903B1

    专利类型

  • 公开/公告日2004-01-30

    原文格式PDF

  • 申请/专利权人 BIOMERIEUX;

    申请/专利号FR19990015312

  • 发明设计人 MONGET DANIEL;DESMONCEAUX MIREILLE;

    申请日1999-12-06

  • 分类号C12Q1/37;C12Q1/04;

  • 国家 FR

  • 入库时间 2022-08-21 22:39:47

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