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New polypeptide from gp41 glycoprotein, useful for prophylactic or therapeutic immunization against human immunodeficiency virus (HIV) infection and for diagnostic detection of HIV
New polypeptide from gp41 glycoprotein, useful for prophylactic or therapeutic immunization against human immunodeficiency virus (HIV) infection and for diagnostic detection of HIV
Polypeptide of formula N-L-C (I), where N and C are amino acids (aa) 25-81 and 112-157 of glycoprotein gp41, respectively, and L is a flexible linker of 2-30 aa, is new. Independent claims are also included for: (1) conjugate (C) of (I) and a carrier protein or peptide; (2) DNA sequence (II) that encodes (I) or (C); (3) vector containing (II); (4) host cell containing the vector of (3); and (5) preparing (I) by expression in cells of (4).
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