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Propionibacterium = flue den Reiki over from a gene encoding an enzyme required for the biosynthesis of vitamin B12
Propionibacterium = flue den Reiki over from a gene encoding an enzyme required for the biosynthesis of vitamin B12
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机译:丙酸杆菌=烟道灵气来自编码维生素B12生物合成所需酶的基因
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摘要
Enzyme encoded by the genes and four novel is disclosed. Exist in the (Propionibacterium freudenreichii) Propionibacterium = flue Den Reiki over, the enzyme is required for the process of at least five of the biosynthetic pathway of vitamin B 12. Enzyme of the four are as follows: a acid Kobirinin, c- diamide synthase; B:: A enzyme has a (cobinamidephosphate guanylyltransferase and cobinamide kinase) function of two 2; C: cobalamin 5-phosphate synthase; and D: adenosyl transferase. That in order to improve an industrial scale production during fermentation of the precursor thereof, or vitamin B 12, and used to transform Propionibacterium host located on propionic acid bacteria shuttle vector genes encoding enzymes of the four possible.
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机译:公开了由该基因编码的酶和四种新颖的酶。存在于(丙酸杆菌)=烟道灵气中,该酶是维生素B 12的生物合成途径中至少五种的过程所必需的。四种的酶如下:a酸性Kobirinin,c-二酰胺合酶; B ::一种酶具有两个(cobinamidephosphate胍基转移酶和cobinamide激酶)功能; C:钴胺素5-磷酸合酶; D:腺苷转移酶。为了提高其前体或维生素B 12 Sub>的发酵过程中的工业规模生产,并用于转化位于丙酸细菌上的丙酸杆菌宿主穿梭编码4种酶的载体基因。
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