METHOD FOR CONTROLLING CELL PROLIFERATION BY UTILIZING NEW FUNCTION OF LEUKOCYTE-RELATED FACTOR MLF1 AND ITS UTILIZATION

摘要

PPROBLEM TO BE SOLVED: To provide a strong cell proliferation-suppressing method clarifying a function of a leukocyte-related factor MLF1 and utilizing the function and to provide a cell proliferation-promoting method by delating the function. PSOLUTION: The method for controlling cell proliferation comprises changing the expression amount of an MLF1 protein which is a leukocyte-related factor or adjusting the function of expressed MLF1 in a cell controlling cell proliferation. When suppressing the cell proliferation, express amount of the MLF1 protein in the cell is increased and when promoting the cell proliferation, express amount of the MLF1 protein in the cell is lowered or the function of the MLF1 protein expressed in the cell is suppressed or inhibited. The method can be applied to various fields such as drug design, medical care and research. PCOPYRIGHT: (C)2005,JPO&NCIPI