METHOD FOR MANUFACTURING terthiophene-3-carboxylic acid compounds of novel, functional conductive terthiophene polymer with a monomer the compound, DNA hybridization detection method using the polymer, and method of manufacturing the probe DNA

摘要

The invention 3 of the new '- carboxy 5,2'; - functional conductive terpolymer having a carboxyl group produced by electrochemical methods as monomers terthiophene compounds, such compounds 5 ', 2 " and also. provides a DNA hybridization method for detecting novel by impedance measurement using the functional conductive polymers such thiophene polymer to provide a method of manufacturing a probe DNA used for DNA hybridization detection method according to the invention . According to the present invention, unlike the prior art, a novel method without using an indicator to detect DNA hybridization using impedance is provided so, in a specific frequency range, which is fixed fabrication of compact sensor system for measuring the impedance are possible, and also. could be applied to the portable DNA sequence hybridization confirmation compact sensor for diagnosis of disease and testing clinical, which, according to the present invention If the selectivity of the complementary sequence to the sequence having a mismatched is very good.