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Methods and compositions for diagnosing ROCHALIMAEA QUINTANA and infection, as well as nucleic acid ROCHALIMAEA HENSELAE of ROCHALIMAEA QUINTANA and ROCHALIMAEA HENSELAE
Methods and compositions for diagnosing ROCHALIMAEA QUINTANA and infection, as well as nucleic acid ROCHALIMAEA HENSELAE of ROCHALIMAEA QUINTANA and ROCHALIMAEA HENSELAE
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机译:诊断罗氏疟原虫和感染的方法和组合物,以及罗氏疟原虫和罗氏疟原虫的核酸
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摘要
A method of diagnosing cat scratch disease and a method of diagnosing bacillary angiomatosis in a subject by detecting the presence of Rochalimaea henselae or an antigenic fragment thereof in the subject is provided. Also provided is a vaccine comprising an immunogenic amount of a nonpathogenic Rochalimaea henselae or an immunogenically specific determinant thereof and a pharmaceutically acceptable carrier. A method of diagnosing Rochalimaea quintana infection in a subject by detecting the presence of a nucleic acid specific to Rochalimaea quintana in a sample from the subject is provided. A purified, 60-kDa heat shock protein of Rochalimaea is provided. Also provided is a 17-kDa antigenic polypeptide of Rochalimaea.
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