embedded imagewherein R1, R2, R3, R4 and R5 are as defined in the description, A signifies —CH═CH— or —C≡C—; and B signifies embedded imagewherein R6 to R26, X and Y are as defined in the specification or a pharmaceutically acceptable salt thereof, for use in pharmaceutical compositions for the treatment or prevention of mGluR5 receptor mediated disorders."/> Phenylethynyl and styryl derivatives of imidazole and fused ring heterocycles
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Phenylethynyl and styryl derivatives of imidazole and fused ring heterocycles

机译:咪唑和稠环杂环的苯乙炔基和苯乙烯基衍生物

摘要

This invention relates to a compound and the use of the compound of the formula embedded imagewherein R1, R2, R3, R4 and R5 are as defined in the description, A signifies —CH═CH— or —C≡C—; and B signifies embedded imagewherein R6 to R26, X and Y are as defined in the specification or a pharmaceutically acceptable salt thereof, for use in pharmaceutical compositions for the treatment or prevention of mGluR5 receptor mediated disorders.
机译:本发明涉及式的化合物及其用途 <图像alt =“嵌入式图像” file =“ US20050131043A1-20050616-C00001.GIF” he =“ 24.47mm” imgContent =“ chem” imgFormat =“ GIF” wi =“ 69.85mm“ /> 其中R 1 ,R 2 ,R 3 ,R 4 和R 5 如说明书中所定义,A表示-CH = CH-或-C = C-;和B表示 <图像alt =“嵌入式图像” file =“ US20050131043A1-20050616-C00002.GIF” he =“ 230.80mm” imgContent =“ chem” imgFormat =“ GIF” wi =“ 69.85mm“ /> 其中R 6 至R 26 ,X和Y如说明书中所定义或其药学上可接受的盐,用于治疗或预防mGluR5受体的药物组合物中介导的疾病。

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