embedded imagewherein R1, R2, R3, R4 and R5 are as defined in the description, A signifies —CH═CH— or —C≡C—; and B signifies embedded imagewherein R6 to R26, X and Y are as defined herein."/> Phenylethynyl and styryl derivatives of imidazole and fused ring heterocycles
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Phenylethynyl and styryl derivatives of imidazole and fused ring heterocycles

机译:咪唑和稠环杂环的苯乙炔基和苯乙烯基衍生物

摘要

This invention relates to the treatment of mGluR5 receptor mediated disorders, which comprises administering to a person in need of treatment a compound having the formula embedded imagewherein R1, R2, R3, R4 and R5 are as defined in the description, A signifies —CH═CH— or —C≡C—; and B signifies embedded imagewherein R6 to R26, X and Y are as defined herein.
机译:本发明涉及mGluR5受体介导的疾病的治疗,包括对需要治疗的人给药具有下式的化合物: <图像alt =“嵌入式图像” file =“ US06927232-20050809-C00001.GIF” he =“ 24.38mm” imgContent =“ chem” imgFormat =“ GIF” wi =“ 53.51mm“ /> 其中R 1 ,R 2 ,R 3 ,R 4 和R 5 如说明书中所定义,A表示-CH = CH-或-C = C-;和B表示 <图像alt =“嵌入式图像” file =“ US06927232-20050809-C00002.GIF” he =“ 161.29mm” imgContent =“ chem” imgFormat =“ GIF” wi =“ 58.84mm“ /> 其中R 6 至R 26 ,X和Y如本文所定义。

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