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Botulinum toxin pharmaceutical compositions with enhanced potency with regard to a reference botulinum toxin pharmaceutical composition

机译：关于参考肉毒杆菌毒素药物组合物具有增强的效力的肉毒杆菌毒素药物组合物

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摘要

A botulinum toxin pharmaceutical formulation free of animal derived proteins, comprising a botulinum toxin and a recombinant albumin, suitable for therapeutic administration to a human patient, and methods for treating patients with various diseases and afflictions with the formulation.

机译：不含动物源蛋白的肉毒杆菌毒素药物制剂，其包含肉毒杆菌毒素和重组白蛋白，适合于对人类患者进行治疗性给药，以及用于治疗患有各种疾病的患者的方法疾病和折磨的配方。 展开▼

著录项

公开/公告号US2005238667A1

专利类型

公开/公告日2005-10-27

原文格式PDF

申请/专利权人 TERRENCE J. HUNT;
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申请/专利号US20050062055

发明设计人 TERRENCE J. HUNT;
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申请日2005-02-17

分类号A61K39/08;

国家 US

入库时间 2022-08-21 22:23:51

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专利

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1. 含有单宁酸的肉毒杆菌毒素药物组合物 [P] . 中国专利： CN112336848A . 2021-02-09

2. 用于治疗足痛疾病的包括肉毒杆菌毒素和透明质酸的药物组合物以及使用其治疗足痛疾病的方法 [P] . 中国专利： CN110913868A . 2020-03-24

3. Method for obtaining a botulinum toxin composition comprising a Biologically Active, Clostridium botulinum and a Culture medium to produce botulinum toxin by Said method and a method for preparing a Pharmaceutical composition substantially free of Animal Product in which I [P] . AR045813A1 . 2005-11-16

机译：通过所述方法获得包含生物活性肉毒梭菌和培养基以产生肉毒杆菌毒素的肉毒杆菌毒素组合物的方法以及制备基本上不含动物产品的药物组合物的方法，其中

4. cell penetrating peptide, polynucleotide, recombinant botulinum toxin penetrating cell protein, recombinant expression vector, bacterium, pharmaceutical composition, cosmetic composition and method for producing a recombinant botulinum toxin cell penetrating protein [P] . BR112016027773A2 . 2017-10-31

机译：细胞穿透肽，多核苷酸，重组肉毒杆菌毒素穿透细胞蛋白，重组表达载体，细菌，药物组合物，化妆品组合物和生产重组肉毒杆菌毒素细胞穿透蛋白的方法

5. Analogs of botulinum toxin and pharmaceutical compositions o f botulinum toxin [P] . AU4746096A . 1996-12-24

机译：肉毒杆菌毒素的类似物和肉毒杆菌毒素的药物组合物

1. Distribution of the Toxin following Medial Rectus Muscular Injection of Botulinum Toxin Gel in Rabbits [J] . Jingchang Chen, Guanghuan Mai, Xinping Yu, 眼科学报（英文版） . 2005,第001期

2. Ultrasound and Electromyography as Guidance Tools for the Botulinum Toxin Therapy in Cervical Dystonia [J] . G. Salazar, S. Ferreiro, M. Fragoso, 行为与脑科学期刊（英文） . 2021,第002期

3. Facial liposuction combined with botulinum toxin type A:A technique for lower facial contouring [J] . Chunjie Li, Xiancheng Wang, Ying Liang, 中国整形与重建外科（英文） . 2021,第003期

4. Clinical Use of Botulinum Toxin in Spasticity Case Description: Severe Adverse Effect with the Use of the Chinese Botulinum Toxin - Prosigne~R [C] . M. Sposito International Society of Physical and Rehabilitation Medicine . 2007

5. A biophysical characterization of botulinum toxin and cholera toxin. [D] . Kuziemko, Geoffrey Matthew. 1997

6. Influence of injection of Chinese botulinum toxin type A on the histomorphology and myosin heavy chain composition of rat gastrocnemius muscles [O] . Bin Hong, Min Chen, Xing-yue Hu 2013

7. Molecular composition of Clostridium botulinum type A progenitor toxins [O] . K Inoue, Y Fujinaga, T Watanabe, 1996

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2. Botulinum toxin associated with fissurectomy and anoplasty for hypertonic chronic anal fissure: A case-control study [J] . Beatrice DOrazio ,Girolamo Geraci ,Fausto Famà . 世界临床病例杂志 . 2021,第032期

3. 可生物降解聚合物纳米胶囊型药物载体及组合胶囊的药物控制释放 [C] . 董岸杰 ,邓联东 . 2005年中德纳米生物技术国际会议 . 2005

4. 抗天花病毒创新药物特考韦瑞三元组合物及其增溶机制的研究 [A] . 李晓溪 . 2016