System and method for determining radius of gyration, molecular weight, and intrinsic viscosity of a polymeric distribution using gel permeation chromatography and light scattering detection

摘要

A system and method for analyzing data from a gel permeation chromatography (GPC) or size exclusion chromatography (SEC) system fro determining a polymeric sample's radius of gyration. Data from two or more detectors is used with a least-squares minimization fit. A novel method includes the simultaneous determination of a sample's radius of gyration using data from a light scattering detector that collects data from at least two incident angles. Detectors within the inventive method include a multi-angle light scattering (LS) detector, viscometer (V) and a refractive index (RI) detector.