Alternatively spliced isoforms of nuclear factor kappa-B, subunit 1 (NFKB1)

摘要

The present invention features nucleic acids and polypeptides encoding two novel splice variant isoforms of nuclear factor kappa-B, subunit 1 (NFKB1). The polynucleotide sequences of NFKB1sv1 and NFKB1sv2 are provided by SEQ ID NO 3 and SEQ ID NO 5, respectively. The amino acid sequences for NFKB1sv1 and NFKB1sv2 are provided by SEQ ID NO 4 and SEQ ID NO 6, respectively. The present invention also provides methods for using NFKB1sv1 and NFKB1sv2 polynucleotides and proteins to screen for compounds that bind to NFKB1sv1 and NFKB1sv2, respectively.