首页> 外国专利> Compounds, methods for preparing a compound and for preventing and / or treating cancer, prodrug, drug, androgen receptor modulator, agent for preventing and / or treating male hypogonadism or climatic disorder, osteoporosis and cancer, and use of a compound.

Compounds, methods for preparing a compound and for preventing and / or treating cancer, prodrug, drug, androgen receptor modulator, agent for preventing and / or treating male hypogonadism or climatic disorder, osteoporosis and cancer, and use of a compound.

机译:化合物,制备化合物和预防和/或治疗癌症的方法,前药,药物和雄激素受体调节剂,预防和/或治疗男性性腺功能减退症或气候障碍,骨质疏松症和癌症的药物,以及化合物的用途。

摘要

"COMPOUNDS, METHODS FOR PREPARING A COMPOUND AND FOR PREVENTING AND / OR TREATING CANCER, PRODUCT, MEDICINE, ANDROGEN RECEIVER MODULATOR, AGENT FOR PREVENTING AND / OR TREATING HYGOGONADISM OR CLIMATE DISORDER, MASCULOS AND ECTEOS, " A compound represented by the general formula (I), wherein ring A represents an optionally substituted 5 to 8 membered ring; ring B represents another optionally substituted 4-10 membered ring; ring C represents another optionally substituted benzene ring; X 12 represents carbon; X 12 represents carbon, oxygen etc .; W represents nitrogen, etc .; Y ^ 11 ^ represents a group represented by the formula CR ^ 2 ^ R ^ 3 39 ^ (where R ^ 2 ^ represents hydrogen, cyano, nitro etc. and R ^ 3 39 ^ represents hydrogen, cyano, nitro etc.); Y ^ 21 ^ represents a group represented by the formula CR ^ 4 ^ R ^ 5 ^ (wherein R ^ 4 ^ represents hydrogen, cyano, nitro etc. and R ^ 5 ^ represents hydrogen, cyano, nitro etc.), etc. ; R ^ 1 ^ represents an electron attraction group; and the symbol ... represents a single bond or double bond. The compound is useful as an androgen receptor modulator. A salt of the compound is also provided.
机译:“化合物,制备化合物以及预防和/或治疗癌症,产品,药物,雄激素受体调节剂的方法,预防和/或治疗hyogogonadism或气候混乱的代理商,混合物和油菜,”用通式表示的化合物( I),其中环A代表任选取代的5至8元环;环B代表另一个任选取代的4-10元环;环C代表另一个任选取代的苯环; X 12代表碳; X 12代表碳,氧等; W代表氮,等等。 Y ^ 11 ^表示由化学式CR ^ 2 ^ R ^ 3 <39> ^表示的基团(其中R ^ 2 ^代表氢,氰基,硝基等,R ^ 3 <39> ^代表氢,氰基,硝基等等。); Y ^ 21 ^代表式CR ^ 4 ^ R ^ 5 ^(其中R ^ 4 ^代表氢,氰基,硝基等,R ^ 5 ^代表氢,氰基,硝基等)。 ; R ^ 1 ^表示电子吸引基;符号...表示单键或双键。该化合物可用作雄激素受体调节剂。还提供了化合物的盐。

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