Isolated human antibody, method of treating an il-1 mediated disease in a patient, pharmaceutical composition, heavy and light chains, and epitope mapping method of a selected antigen

摘要

"ISOLATED HUMAN ANTIBODY, METHOD OF TREATING ILL-1 MEDIATED DISEASE IN A PATIENT, PHARMACEUTICAL COMPOSITION, HEAVY AND LIGHT CHAINS, AND A SELECTED ANTIGEN EPITOPO MAPPING METHOD". Antibodies that interact with interleukin-1 type 1 receptor (IL-1R1) are described. Methods of treating IL-1 mediated diseases by administering a pharmaceutically effective amount of antibodies to IL-1R1 are described. Methods of detecting the amount of IL-1R1 in a sample using antibodies to IL-1R1.